Medical Genetics 3rd
medical genetics 3rd
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![]() Lecture Notes Medical Genetics 3rd Revised edition US $42.58
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![]() Medical Genetics by Jorde 3rd ed US $2.00
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Blood In Stool - 7 Root Causes In The Colon
Blood in stool is often discovered with some dismay, accompanied suitably by exclamations of bloody (the adjective, not the expletive). Stools are coated with scarlet red blood droplets. Crimson red blotches of blood blemishes the toilet tissue. Bright red spots of blood dribble into the toilet bowl or down the legs. A sudden pang of bewilderment causes our hearts to jump a beat or two.
Perplexity is understandable but panic is unwarranted at this stage as the rectal bleeding or hemorrhaging could be attributed to any of 7 possible causes arising from the colon. Mindful attention to ensure early diagnosis and correct treatment will lighten any distracting lifestyle changes as the greater number of the 7 causes are treatable. Watchfulness is the order of the day. Begin tracking closely. If incessant bleeding and pain drags on for more than a week, consult a doctor immediately.
The problem can be solved by relevant treatment once accurate diagnosis spots the precise illness. More overwhelmingly, blood in stool may find its root cause in some kind of cancer.
Melena and Hematochezia
Medical circles refer to the bleeding as hematochezia (bright red or maroon colored blood) or melena (black colored tarry or sticky stools) or typically the less technical term, rectal bleeding. Rectal bleeding may leave via the rectum but the root cause may be in the colon (large intestine) or the small intestine. In the colon, the 7 known causes are cancer, colon polyps, diverticulosis, Crohn's disease, ulcerative colitis, intestinal ischemia and peptic ulcer.
Colorectal Cancer
Ranked the 3rd most frequent cancer in the world, colorectal cancer is also the 3rd most prevalent cause of cancer-related deaths, registering up to 640,000 annually. It is the reason why one must consult a medical professional for constant blood in stool.
Malignant growths in the colon, appendix and rectum are classified as colorectal cancer. Found mainly via colonoscopy (visual diagnosis with a camera mounted on a flexible tube inserted through the anus), colorectal cancer treatment involves surgical removal accompanied by chemotherapy. Timely detection often leads to a total cure. Those over 50 and those with family history of cancers are grouped under the higher risk group. Colorectal cancer is gender blind, distressing both women and men, with no noticeable bias for either sex.
Another critical piece of information needs to be highlighted. Contrary to popular internet literature, colorectal cancer typically results in occult (not visible to the naked eye) blood in feces i.e it is NOT a regular cause of visible blood in stool! Colorectal cancer causes occult bleeding i.e. blood is not perceptible to the naked eye, and special tests are required for detection. This is according to the University of Michigan Health System. Diarrhea, constipation, abdominal pain, weight loss, appetite loss and incessant fatigue are accompanying symptoms to watch out for.
Colon Polyp
Affixing on the walls of the intestines or the rectum, polyps are mainly benign and may be raised or flat. Those above 50 years of age and with a family history of polyps and colorectal cancer are prone to polyps. Smoking, alcohol, obesity and lack of exercise are contributory causal factors. So it seems that the real cause is unknown.
Whilst benign, polyps are usually excised during colonoscopy as they can turn malignant. Many people who have polyps demonstrate no symptoms at all. But in some people, blood in stool is present.
Diverticulosis
Pouches (diverticula) stretching from the colon wall is characteristic of diverticulosis. Abnormal colon pressure is postulated to be the cause of diverticula growth. A lack of dietary fiber worsens diverticulosis. Diverticulitis is an infection that may arise if food gets trapped in diverticula. Complications from diverticulitis can occur if a diseased diverticulum bursts open and releases bacteria to the abdominal cavity lining. The possibly deadly peritonitis can materialise.
Many people with diverticulosis do not see any symptoms at all. Some may feel symptoms of constipation, bloating and mild cramps. More serious symptoms include vomiting, nausea and rectal bleeding. The prospect of peritonitis attest to the urgency that blood in stool should in the first instance be examined by a doctor. Effective diagnosis of diverticulitis can be achieved with a CT (computed tomography) scan.
Ulcerative Colitis
Colitis is categorized as an inflammatory bowel disease, a group of inflammatory conditions of the small intestine and the large intestine (colon). Inflammation is a robust reaction of the body when its tissues are damaged. Like a charging locomotive, inflammation delivers its payload of cured tissue but if not terminated it causes tissue harm instead. Ulcerative colitis is caused by ulcers which are wearing away of the mucous membrane lining.
Apart from other symptoms, blood in stool is common. The risk of peritonitis from colitis is the key reason for determining it as the cause of rectal bleeding.
Crohn's Disease
Crohn's disease is an inflammatory bowel disease but is also an auto-immune disease in which the body's immune system turns on the gastrointestinal tract inducing destructive inflammation. From the mouth to the anus, Crohn's disease can happen in any part of the gastrointestinal tract. But it usually affects the small and large intestine (colon).
Exact causes are not known but it is believed to be due to one or all of several factors including industrial environmental exposure, genetic makeup and smoking. The symptoms are blood in stool, abdominal cramps, severe bloody diarrhea, blood on toilet tissue or in the toilet bowl, fever and weight loss.
Intermittently recurrences throughout life or permanent remission both typify Crohn's disease, also referred to as granulomatous colitis. As of now, there is no known surgical or pharmaceutical solution for Crohn's disease. Early detection is essential for effective control of the symptoms and retarding recurrences.
Intestinal Ischemia
The suppression of blood supply to any part of the body is termed as ischemia. Tissue damage results due to the deprivation of nutrients and oxygen by dysfunctional blood vessels. Intestinal ischemia is the lack of blood supply causing inflammation of the large intestine; a consequence of blood clots, blood vessel constriction and general high blood pressure.
Symptoms include blood in stool, abdominal bloating, abdominal cramps, violent bowel movements, nausea, fever and weight loss. Immediate medical attention is required to restore intestinal blood supply if there is serious unrelenting pain. Surgery may be necessary to eradicate damaged tissue, blockages and blood clots and to get around blocked blood vessels. To inhibit clots and infections, respective medication includes anticoagulants and antibiotics.
Peptic Ulcer
An highly painful ulcer, this is found in the gastrointestinal tract. An ulcer is an deterioration of the mucosal membrane that is at least 0.5cm in diameter. Peptic ulcers normally manifest in the duodenum (initial part of the small intestine) and not in the stomach as commonly believed. Peptic ulcers are largely conjectured to be caused by a bacterium that inflicts chronic gastritis.
Symptoms include blood in stool (melena), vomiting of blood, appetite and weight loss, bloating, nausea and more seriously, intestinal perforation. Peritonitis, possibly life-threatening, may develop and entail emergency surgery. Treatment of easier cases incorporates antibiotics to resist the bacteria and antacids to moderate the acidity.
Hemorrhoids
Documented above are 7 very good reasons for consulting a doctor for a definite diagnosis when rectal bleeding is experienced. Rapid recovery is achievable with early detection, proper treatment and medication.
Having come this far, you may find relief, ironically, in finding that the most prevalent causes of blood in stool are hemorrhoids.
Further Reading
If you are interested in finding more about this topic, we have a related post on Bowel Movement Bleeding - Six Possible Causes Of Rectal Bleeding at our site. Do check this out.
About the Author
Rachel Rich is an passionate supporter of natural remedies and cures before fabricated pharmaceutical prescriptions as these often have ancillary effects that are not well made public. Her active cynicism about big pharma's commercial pronouncements translates into affirmative steadfastness that compels her into very exhaustive fact-finding before purchasing any product. Her decisions are featured at The Treatment of Hemorrhoid Site.
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Lecture Notes: Medical Genetics, 3rd Edition $44.8 No Synopsis Available |
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Medical Genetics $3.94 This book has been designed to provide medical students with an understanding of the basic principles of human genetics as they relate to clinical practice. Taking into account the recent recommendations on teaching from the American and British Societies of Human Genetics, each of the initial chapters focuses on a traditional cornerstone of human genetics (molecular genetics, cytogenetics, Mendelian inheritance, polygenic inheritance, population genetics) with a major emphasis on clinical relevance. These are followed by consideration of subjects of specific medical importance such as the haemoglobinopathies, developmental genetics, cancer genetics and pharmacogenetics, with due attention to topical and evolving issues such as pharmacogenomics, gene therapy and therapeutic cloning. The final chapters provide an explanation of the genetically related clinical skills and competencies expected of a medical student, together with an overview of the principles of clinical genetics, a rapidly developing clinical specialty which now impinges on almost every aspect of medical practice. Over 150 illustrations have been included to demonstrate important principles and commonly encountered genetic disorders. Each chapter contains a brief review of a major landmark publication to provide a historical context for more contemporary developments. To help sustain the student's interest and to emphasise the potential importance of genetics in medicine, large numbers of clinically related vignettes have been included covering controversial issues, such as gene patenting and the UK Biobank, together with case histories and brief biographies of famous figures from history and the arts who have suffered from, and successfully coped with, a genetic disorder. |
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Genetics $50 About the Book: Endeavours to make this seemingly difficult subject understandable and enjoyable for the readers. It provides an account of classical and modern genetics with new developments in the field. The scope of each chapter has been broadened enough to provide information on historical landmarks as well as of new facts from current issues of major journals. Chapters on gene transcription, regulation, human genetics, recombinant DNA and genomics have been given special attention to create awareness about future areas in this growing field. Experimental work is supported by methodologies and illustrations. The text is useful for students pursuing courses in cell and molecular biology, biophysics, anthropology and agricultural sciences at universities, medical colleges and similar institutions. Contents: The Pre-Mendelian Era and Mendelism Interaction of Genes Environment and Gene Expression Quantitative or Polygenic Inheritance Multiple Alleles Cell Division and Chromosome Theory of Inheritance Chi-Square Test and Probability Linkage, Recombination and Gene Mapping Extranuclear Transmission of Traits The Genetic Control of Sex Variations in Chromosome Number Variations in Chromosome Structure Nature of the Genetic Material The Structure and Replication of DNA Gene Transcription and Translation into Proteins Genetic Regulation in Prokaryotes and Eukaryotes Genetics of Bacteria Genetics of Viruses The Eukaryotic Chromosome Mutations Human Genetics Fine Structure of the Gene Recombinant DNA Technology Applications of Recombinant DNA Technology Genomics Populations and Gene Frequencies Origin of Life-Evolution of Man |
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Lecture Notes: Medical Genetics $43.25 Lecture Notes: Medical Genetics provides a concise and straightforward introduction to medical genetics. The text aims to give students a fundamental understanding of the science of genetics and molecular medicine and a knowledge of the core clinical conditions caused by genetic abnormalities. Previously titled Lecture Notes on Molecular Medicine, this new edition has a greater focus on clinical genetics while continuing to provide core information on the scientific background and advances in genetics and molecular medicine. Thoroughly revised and updated, Lecture Notes: Medical Genetics is an invaluable primer for any science student new to molecular biology and genetics, and an excellent resource for medical students, junior doctors and practicing clinicians requiring an understanding of scientific advances in the field and their impact on clinical medicine. |
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Essential Medical Genetics $4.2 Essential Medical Genetics gives a balanced introduction to the basic principles of genetics and how it is applied to the understanding and treatment of diseases with a genetic component. Divided into two sections, basic principles and clinical applications, it covers the information that medical students are taught at the preclinical and clinical levels. This book has been written for clinicians, scientists, counselors and teachers--and any other professionals desiring an understanding of modern medical genetics. |
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Molecular Genetics of Bacteria $53.98 This landmark volume provides the single most comprehensive and authoritative textbook on bacterial molecular genetics. Perfect for advanced undergraduate and graduate-level courses, the text presents the latest research on the subject in a clearly written and well-illustrated style. It provides descriptive background information, detailed experimental methods, examples of genetic analyses, and advanced material relevant to current applications of molecular genetics. While providing a deep understanding of bacterial molecular genetics, the material is integrated with biochemical, genomic, and structural information to broaden understanding. The approach centers on the most-studied bacteria, Escherichia coli and Bacillus subtilis. In addition, examples from other bacteria with medical, ecological, or biotechnological significance are covered throughout the text. The material in each chapter has been substantially revised and rewritten and reflects exciting developments in the field of bacterial molecular genetics and its relationship to other fields, including genetics, biotechnology, and bioengineering. Molecular Genetics of Bacteria, 3rd Edition is organized like the two previous editions. Each chapter contains a summary of main points, descriptions of significant experiments, a set of discussion questions and a problem set (with answers to both at the back of the book), and a list of suggested readings--all updated to reflect the most recent advances in the field. Additionally, text boxes present intriguing information on each topic without interrupting the continuity of the text. This new edition will be invaluable to anyone working in the fields of microbiology, genetics, biochemistry, bioengineering, medicine, molecular biology, and biotechnology. It is also essential reading for scientists in all fields of biology, many of whom depend upon the concepts and techniques covered in this book. |
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Medical Genetics at a Glance $3.94 "Medical Genetics at a Glance" is a concise, well-illustrated and accessible genetics textbook. It follows the now familiar, easy-to-use, double page spread format of the "At a Glance" series. Each double page presents clear, memorable diagrams that illustrate essential information with accompanying text that covers key topics and issues in more detail. Structured into three distinct sections, "Medical Genetics at a Glance" takes the student through developmental biology, medical genetics and the clinical application of genetics. The first section focuses on basic biological concepts such as cell and chromosome structure, molecular biology and the cell cycle, as well as human embryonic development and sexual maturation. The second section applies these principles to medicine through the essential 'laws' of inheritance, the chromosome anomalies, multifactorial inheritance, normal polymorphism and gene frequency, then moving on to gene mapping, mutagenesis, cancer and immunogenetics. The final section addresses the clinical application of the above principles in pedigree drawing and molecular diagnostic procedures based on the human gene map, PCR and Southern techniques, risk assessment, genetic counselling, gene therapy and much more. "Medical Genetics at a Glance" is an ideal resource that fits the budget and reading time of medical students and those seeking a quick, thorough introduction to this fast moving field. It can be used as primary or supplementary reading in a lecture-based course and is perfect for exam preparation. |
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Emery's Elements of Medical Genetics $55.3 Master the genetics you need to know with the updated 14th Edition of Emery's Elements of Medical Genetics by Drs. Peter Turnpenny and Sian Ellard. Review the field's latest and most important topics with user-friendly coverage designed to help you better understand and apply the basic principles of genetics to clinical situations. Learning is easy with the aid of clear, full-color illustrative diagrams, a wealth of clinical photographs of genetic diseases, multiple-choice and case-based review questions, end-of-chapter summaries, and convenient online access at www.studentconsult.com. With this highly visual, award-winning classic in your hands, you have all the genetics knowledge you need for exams or practice. |
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Medical Genetics [With Access Code] $43.42 Medical Genetics is the clearest and most concise text on the subject, providing state-of-the-art coverage of clinically relevant molecular genetics. Lynn B. Jorde, PhD; John C. Carey, MD; and Michael J. Bamshad, MD integrate recent developments with clinical practice and emphasize the central principles of genetics and their clinical applications. Now in full color, this edition provides you with the stunning visual clarity so important in this field. Get the very latest on hot topics like gene identification, cancer genetics, gene testing and gene therapy, common diseases, ethical and social issues, personalized medicine, and much more. With Student Consult access, you'll get the full text online, along with images, 150 USMLE-style questions, and the clinical commentary and patient/family vignette boxes from the text-collated by chapter-for review. The accompanying Evolve site provides additional faculty notes, higher resolution images, 150 multiple choice questions, and 100 sample problems and essay questions. In other words, this is an indispensable resource that should be on every reading list. |
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Essential Medical Genetics (5th Edition) $79.92 Essential Medical Genetics gives a balanced introduction to the basic principles of genetics and how it is applied to the understanding and treatment of diseases with a genetic component. Divided into two sections, basic principles and clinical applications, it covers the information that medical students are taught at the preclinical and clinical levels. This book has been written for clinicians, scientists, counselors and teachersand any other professionals desiring an understanding of modern medical genetics. Author: Connor, J. Michael/ Connor, Michael/ Smith, M. Ferguson Series Title: Essentials Binding Type: Paperback Number of Pages: 248 Publication Date: 1997/04/29 Language: English Dimensions: 11.05 x 8.26 x 0.60 inches |
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Essentials of Medical Genetics for Health Professionals $57.62 Essentials of Medical Genetics for Health Professionals is a concise, accessible introduction to medical genetics for all health professions students. Even with limited exposure to genetics, students can use the accelerated approach in this text to attain a base foundation of genetics knowledge. This book begins with a review of chromosomes, DNA, RNA, protein synthesis, and inheritance patterns and continues with a clinical focus based on understanding different disease processes. A variety of genetic diseases are explored, including what is known about the genetics involved, the signs and symptoms of the disease, and the treatment options available. This book also covers diagnostic techniques and an overview of embryonic development and teratogens. The roles of genetic counseling and screening, as well as the ethical and legal issues related to genetic screening and genetic testing are also discussed. Complete with stated objectives, definition of key terms, references, chapter summaries and end of chapter review questions with answers, each chapter is organized for optimal learning. Essentials of Medical Genetics for Health Professionals will not only have application in the classroom setting for health professions or medical students, but practicing clinicians such as physician assistants, nurse practitioners, and physicians who want to learn more or revisit genetics will also find this book a valuable, useful resource. |
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Advances in genetics $156 The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge gained from genetics research. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. |
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Human Genetics $199 Presents an exposition of the concepts, results, and problems underlying theory and practice in human and medical genetics. This title includes chapters on such topics as epigenetics, pharmacogenetics, gene therapy, cloning, and genetic epidemiology, and databases for basic and clinical genetics. |
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Advances in Genetics $161 The field of Genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge gained from genetics research. Advances in Genetics continually publishes important, timely reviews from leaders in the field that cover a broad range of topics of interest to geneticists and their colleagues in affiliated disciplines. Important, timely reviews from leaders in the field. Cover a broad range of topics of interest to geneticists and their colleagues in affiliated disciplines. |
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Horse Genetics $68.99 Tired of trying to relate pea plants, fruit flies and mice to practical horse breeding? Textbooks of general genetics rarely mention horses. Consequently our knowledge of horse genes lags well behind that of other domestic animals. Horse Genetics is one of the first books to provide a comprehensive overview of genetic principles using horses as the primary examples. The author, who has both practical and academic experience in the subject, provides jargon-free facts and ideas in the field of genetics as it relates to horses. Well-documented topics such as coat color are covered as well as parentage testing, medical genetics and gene mapping. This book presents a unique and up-to-date review of horse genetics with a clear vision for future research. Sure to become a classic, Horse Genetics is a valuable addition to the field of equine science and every modern equine practitioner's library. |
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Medical Genetics: With STUDENT CONSULT Online Access, 4e (MEDICAL GENETICS ( JORDE)) $30.51 Medical Genetics is the clearest and most concise text on the subject, providing state-of-the-art coverage of clinically relevant molecular genetics. Lynn B. Jorde, PhD; John C. Carey, MD; and Michael J. Bamshad, MD integrate recent developments with clinical practice and emphasize the central principles of genetics and their clinical applications. Now in full color, this edition provides you with the stunning visual clarity so important in this field. Get the very latest on hot topics like gene identification, cancer genetics, gene testing and gene therapy, common diseases, ethical and social issues, personalized medicine, and much more. With Student Consult access, you'll get the full text online, along with images, 150 USMLE-style questions, and the clinical commentary and patient/family vignette boxes from the text-collated by chapter-for review. The accompanying Evolve site provides additional faculty notes, higher resolution images, 150 multiple choice questions, and 100 sample problems and essay questions. In other words, this is an indispensable resource that should be on every reading list.Includes access to the complete text and images online at studentconsult.com along with 150 additional USMLE-style questions for self-assessment. Features mini-summaries, study questions, suggested reading, and a detailed glossary to supplement and reinforce what you learn from the text. Demonstrates clinical relevance through over 230 photographs, illustrations, and tables, along with boxes containing patient/family vignettes. FOR FACULTY: Supplements the text with online access to EVOLVE Resources. Contains additional faculty notes, higher resolution images, 150 multiple choice questions, and 100 sample problems and essay questions online for teaching purposes. Enhances the visual impact of the material with full-color illustrations throughout the text for easier and more effective learning and retention. Presents a new chapter on genomics and personalized medicine for the latest on these hot topics. Provides you with the latest knowledge and research on gene identification, cancer genetics, gene testing and gene therapy, common disorders, ethical and social issues, and much more so you can keep up with current developments in genetics. Includes study questions at the end of every chapter so you can test yourself and retain the material. Features additional clinically commentary boxes throughout the text to show the relevance of genetics to everyday patient problems to prepare you for problem-based integrated courses. |
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Introduction to Population Genetics $133.85 Making the theory of population genetics relevant to readers, this book explains the related mathematics with a logical organization. It presents the quantitative aspects of population genetics, and employs examples of human genetics, medical evolution, human evolution, and endangered species. For an introduction to, and understanding of, population genetics. |
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Computational Methods for Genetics of Complex Traits $156 The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics reasearch. This thematic volume of Advances in Genetics looks at Computational Methods for Genetics of Complex traits. The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics reasearch. This thematic volume of Advances in Genetics looks at Computational Methods for Genetics of Complex traits. |
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Advances in Genetics Volume 58 $3.94 The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes imporatnt reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. |
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Biochemistry & Genetics $59.85 LANGE FlashCardsBiochemistry & GeneticsSuzanne J. BaronChristoph I. LeeSuper-Power your test prep!150 cards for course review and USMLE preparationBlast through Biochem and Genetics!Conquer biochemistry and genetics exams and the USMLE Step 1 with LANGE FlashCards?the most effective portable learning tool ever!? Rapid-study Power Pack? Concise and complete coverage of all major processes and principles? Key disease facts (etiology, pathology/pathophysiology, clinical manifestations, and treatment) on every card? Clinical vignettes on each card? Concise yet complete coverage of biochem and genetics courses? Perfect for disease comparisons? Created by medical students for medical studentsVisit: www.accessmedbooks.com |
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